Detailed Doxycycline dosage information for adults and children. Please enable it to take advantage of the complete set of features! Doxycycline has been considered a safe broad-spectrum antibiotic for patients with renal failure.
No correlation between serum concentration and degree of renal failure was found. Doxycycline in doses of 200 mg. the first day followed by 100 mg. every 24 hours for 6 days was administered. Magliari F, Mastrangelo F, Lopez T, Rizzelli S, Manisco G, Corliano C.Pediatr Infect Dis J. Includes dosages for Bacterial Infection, Urinary Tract Infection, Acne and more; plus renal, liver and dialysis adjustments. The serum concentration of active drug was measured twice daily, and the urinary drug excretion followed during the study. Review of the literature suggests that occasional patients may have impairment of the nonrenal excretory pathway for doxycycline. Silverchair Information Systems 2007 Feb;26(2):183-5. doi: 10.1097/01.inf.0000250687.05055.67.Drugs. Uncomplicated gonococcal infections in adults (except anorectal infections in men): 100 mg, by mouth, twice a day for 7 days. Each drug was given as a single, 200‐mg intravenous infusion We report here a patient with stable chronic renal failure whose renal function acutely and reversibly deteriorated coincident with a 14-day course of doxycycline. 1979 Nov;18(5):377-91. doi: 10.2165/00003495-197918050-00003. The individual serum levels of doxycycline varied considerably, but there was no tendency to accumulation of active drug in serum. Glomerular filtration rate and effective renal plasma flow, defined as the clearance ofinulin and the clearance of PAH, respectively, were measured before and after the administration period. Download Citation | Doxycycline in renal failure | Twelve patients with grossly impaired renal function were studied.